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22) resulted in a 77% increase in clarithromycin auc and a 100% decrease in the auc of 14-oh clarithromycin. The 14-oh clarithromycin is twice as active against haemophilus influenzae microorganisms as the parent compound.
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Other drugs besides clarithromycin, which may affect the heart rhythm (qtc prolongation in the ekg), include dofetilide, disopyramide, quinidine, droperidol, sotalol, procainamide, and sparfloxacin among others.
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One-third as many clarithromycin-treated patients reported diarrhea as did amoxicillin. With a 500 mg every 8 to 12 hours dosing, the peak steady-state concentration of 14-oh clarithromycin is slightly higher (up to 1 How taken wellbutrin sr comes as a tablet to take it orally.
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